In this episode, we will explore the introduction of Western style surgery into feudal Japan, during the period of isolation, that lasted from 1639 to 1853. During this time, only a few of the European powers had access to Japan, and for most of that time, it was Holland alone. The Dutch, through trade by the Dutch East Indies Company, held a monopoly on trade with Japan, and came to greatly influence their practice of surgery. Along the way, we'll meet some of these surgeons, as well as a Japanese surgeon who was able to perform major surgery on patients while they slept, a breakthrough that beat the events of the Ether Dome by more than 40 years!